Capacity for Development: New Solutions to Old Problems

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For thousands of years it has been the traditional land of the Wendat, the Seneca, and most recently, the Mississauga of the Credit River. Today it is still the home to many Indigenous people from across Turtle Island and we are grateful to have the opportunity to be on this land. Come along on one and see if TFN membership might be right for you. Walks, lectures, stewardship, citizen science, our newsletter, and so much more await. Explore the benefits of membership and join today.

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[] Fluctuations around Hartree states in the mean-field regime

Contact Us Privacy Policy. A penicillin-sensitive EIS structure with a high long-term stability was fabricated by immobilising the enzyme penicillinase with a heterobifunctional cross-linker [ 35 - 38 ]. Enzyme-based LAPS for the determination of urea and butyrylcholine have been elaborated with photocurable polymeric enzyme membranes of urease and BuChE butyrylcholinesterase , respectively [ 48 ]. The subject of miniaturised multi-sensor systems, i. Usually, a large number of single-function sensors are combined that suffer from the drawback of different sensitive layers and transducer principles, which have to be optimised and operated at the same time.

As an alternative, in our research experiment, a hybrid sensor module that is based on an identical transducer principle has been suggested. Consequently, the amount of bio- chemical and physical information is higher than the number of sensors that are present in the module.

For the measuring principle, the ISFETs within the hybrid sensor module are operated in the constant charge mode [ 55 - 58 ]. For example, insects are known for their extraordinary sensory abilities. In this approach, the voltage generated in the antenna upon smelling a certain odour concentration is used to modify the drain current of the transistor.

They are summarised in Table 1.

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Some of these sensors e. With regard to possible practical applications, e. The penicillin-sensitive EIS sensor has been proven for the penicillin detection in fermentation processes; the pH-sensitive EIS sensor has been tested in food technology, especially with respect to a feasible CIP cleaning in process procedure. In addition, momentary work deals with new concepts of integrated miniaturised reference electrodes in silicon technology for potentiometric sensor systems. The author gratefully thanks Y.


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Ermolenko, M. Keusgen, J. Kloock, H. Mourzina, A. Mulchandani, A. Poghossian, P. Schroth, J. Schultze, S. Simonis, A.

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Wagner, J. Wang and T. National Center for Biotechnology Information , U. Journal List Sensors Basel v.

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Sensors Basel. Michael J. Author information Article notes Copyright and License information Disclaimer. Email: ed. Received Jun 1; Accepted Jan Abstract Microfabricated semiconductor devices are becoming increasingly relevant, also for the detection of biological and chemical quantities. Introduction The rapid development of semiconductor micro- and nano-technologies has stimulated the creation of new sensor concepts that combines both chemical and biological recognition processes with silicon chip manufacturing.

This paper gives an overview on different kinds of silicon-type field-effect chemical sensor and biosensor approaches that are based on: thin dielectric materials in the nm-scale for ion-selective sensing e. Generally, the following basic mechanisms of potential generation can be considered for this type of electrochemical sensor [ 6 ]: -.

Open in a separate window. Figure 1. Figure 2. Figure 3. Figure 4.

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Table 1. Acknowledgments The author gratefully thanks Y. References 1. Shoji S. In: Micro total analysis systems, Sensors Update.

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Baltes H. Wiley-VCH; Weinheim: Micro total analysis systems: microfluidic aspects, integration concept and applications. Topics in Current Chemistry. Klein M. Characterization of ion-sensitive layer systems with a C V measurement method operating at constant capacitance.

Actuators B. Hafeman D. Light-addressable potentiometric sensor for biochemical systems. Bergveld P. Development of an ion-sensitive solid-state device for europhysiological measurements. IEEE Trans. Poghossian A. Sensors and Actuators B. Penicillin detection by means of silicon-based field-effect structures. Sensors and Materials.

Yoshinobu T. In: The measurement, Instrumentation and Sensors Handbook. Webster J. Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors? Pulsed laser deposition — an innovative technique for preparing inorganic thin films.